23
August
2008
Dr Coleman just received the first shipment of Evolence to his office in TriBeCa. Even though the FDA approved this innovative form of collagen as a dermal filler in June 2008, Evolence just now being delivered to offices.
The Aesthetics Group of OrthoNeutrogena, a division of Johnson & Johnson, will only sell Evolence to a physician who has been trained in its use. Dr. Coleman flew to Grand Cayman earlier this year to inject Evolence into patients, and he now will train other physicians in the use of Evolence.
The pricing for Evolence is similar to Radiesse, Restylane and Juvaderm; however, more Evolence may be necessary to obtain the initial correction. This increased expense is offset however, by the longer duration of the correction with Evolence. The FDA trials in the US were only for six months, so the press release for the FDA only mentions six months duration of the correction. However, the European Evolence website says that the results last up to twelve months; and the experience of injectors in Europe is that it lasts even longer.
Above are photographs of one of Dr. Coleman’s patients he treated with Evolence in the nasolabial folds, lips and around the chin. This patient experienced minimal bruising and surprisingly little swelling as seen at twelve hours (middle photograph). The right photo is one month after the procedure and demonstrates notable softening of the deep wrinkles and folds.
More photos soon from Dr. Coleman. In the meantime, please look at the Evolence before and after gallery for more examples.
Posted by office of SR Coleman
© Coleman 2008
Posted: Facial fillers
18
August
2008
There is a new filler on the market! An innovative form of collagen for injection, Evolence was approved by the FDA in June 2008 and will be available in the US soon.
Collagen Corporation introduced the original collagen for injection into the skin, Zyderm and Zyplast, over 25 years ago. They were made from cows (bovine), lasted two to five months after injection and required skin testing to determine potential reactions to the product. Evolence is made from pigs (porcine), can last over a year and requires no skin testing. Porcine collagen is more similar to human collagen, and has been used safely in the production of heart valves for years.
Hyaluronic acid based products like Restylane and Juvaderm produce their effect by attracting water to the surrounding tissues. The advantage of a collagen-based product such as Evolence is that it mimics human collagen by providing a matrix like support structure for the skin.
Colbar of Israel asked me to be on their medical advisory board over three years ago. I met with the executive from the company who I knew from Q-med and the Restylane products. She said that the company wanted me to be involved in the evaluation and development of Evolence. She explained the GlymatricTM technology used to link the collagen dramatically increased its stability and longevity.
Even though I did not join their board, as I attended many plastic surgery meetings in Europe and Asia over the next years, I heard many positive comments from the physicians using Evolence: They claimed less bruising and swelling and noted a different effect than filling with hyaluronic acid fillers. Finally and perhaps most importantly, the European and Asian physicians claimed that Evolence lasted much longer than other non-permanent fillers, up to two years.
I was not surprised when over a year ago I heard that Johnson & Johnson acquired Evolence for international distribution by the Aesthetics Group of OrthoNeutrogena. Another executive from Q-med who now works for Johnson & Johnson invited me early this year to fly to Cayman to inject Evolence in patients, so I could understand better the advantages of the product.
In the Cayman Island, I was able to perform injections into many areas of the face, using both Evolence and Evolence Breeze (the formulation for lips). The products exceeded my expectations, and I was pleased to hear that Evolence was approved by the FDA in June 2008 and will be available in the US soon. Evolence Breeze will probably be available in the near future.
The patients that I have already treated with Evolence have apparently had great results. I think it is a welcome addition to the tools in my practice for rejuvenating the face.
Before and after photos for Evolence coming soon.
Posted by SR Coleman
© Coleman 2008
Posted: Facial fillers
